2. Signaling Pathways
  3. Epigenetics
  4. YTHDF
  5. YTHDF Degrader

YTHDF Degrader

YTHDF Isoform Comparison

YTHDF Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-137341
    SK-3-91
    		Degrader 98.47%
    SK-3-91 is a PROTAC-type multi-kinase degrader that can jointly induce the degradation of the largest number of unique kinases (more than 125 unique kinases). SK-3-91 induces protein degradation through the ubiquitin biotinylation (E-STUB) pathway. SK-3-91 degrades YTHDF2. SK-3-91 inhibits cell proliferation and induces morphological changes. (Pink: TAE648 ligand (HY-169396); Blue: E3 ligase ligand (HY-131717); Black: Linker (HY-140819). The E3 ligase ligand and linker can form a conjugate (HY-169397)).