1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite NADPH Oxidase
  3. Ubiquinone-1

Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166).

For research use only. We do not sell to patients.

Ubiquinone-1 Chemical Structure

Ubiquinone-1 Chemical Structure

CAS No. : 727-81-1

Size Price Stock Quantity
Solvent
1 mg (40 mM * 100 μL in Ethanol) In-stock
Solvent
5 mg (40 mM * 500 μL in Ethanol) In-stock
Solvent
10 mg (40 mM * 1 mL in Ethanol) In-stock
Solvent
25 mg (40 mM * 2.5 mL in Ethanol) In-stock
Solvent
50 mg (40 mM * 5 mL in Ethanol) In-stock
Solvent
100 mg (40 mM * 10 mL in Ethanol) In-stock

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Description

Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166)[1][2][3][4][5].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Ubiquinone-1 (60 µM) induces external deamino-NADH oxidation in potato tuber mitochondria by altering the specificity of an external Rotenone (HY-B1756)-insensitive NADH dehydrogenase[1].
Ubiquinone-1 (100 µM) is rapidly and efficiently reduced to extracellularly detectable ubiquinol-1 by whole blood, isolated erythrocytes, and human hepatoma HepG2 cells[3].
Ubiquinone-1 (150 µM) is reduced by NADPH oxidase of guinea pig macrophages under anaerobic conditions[4].
Ubiquinone-1 is reduced by Ascorbic acid (HY-B0166) in a molecular oxygen concentration-controlled process[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

250.29

Formula

C14H18O4

CAS No.
Appearance

Liquid

Color

Orange to red

SMILES

O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)\C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Solvent & Solubility
In Vitro: 

Ethanol : 10 mg/mL (39.95 mM; ultrasonic and warming and heat to 60°C)

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 3.9954 mL 19.9768 mL 39.9537 mL 99.8841 mL
5 mM 0.7991 mL 3.9954 mL 7.9907 mL 19.9768 mL
10 mM 0.3995 mL 1.9977 mL 3.9954 mL 9.9884 mL
15 mM 0.2664 mL 1.3318 mL 2.6636 mL 6.6589 mL
20 mM 0.1998 mL 0.9988 mL 1.9977 mL 4.9942 mL
25 mM 0.1598 mL 0.7991 mL 1.5981 mL 3.9954 mL
30 mM 0.1332 mL 0.6659 mL 1.3318 mL 3.3295 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ubiquinone-1
Cat. No.:
HY-113449
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