2. Reference Standards
  3. Natural Product Standards
  4. Quinones

Quinones

Quinones represent a class of compounds that are widely distributed in nature. They are found in a wide variety of plants. They are also present in fungi, bacteria and in small amounts in animals. Quinones have a common basic structural pattern: an ortho or a para substituted dione conjugated either to an aromatic nucleus (benzoquinones) or to a condensed polycyclic aromatic system, such as Benzene quinones, Naphthalene quinones, Phenanthrenequinones and Anthraquinones. Quinones have potential biological activities for antioxidant, anti-inflammatory, antibiotic, anti-microbial, and anti-cancer activities. Anthraquinone derivatives, an important subclass of quinones show a wide array of pharmacological activities including laxative, anti-cancer, anti-inflammatory, anti-arthritic, anti-fungal, anti-bacterial, antiviral, anti-platelet aggregation and neuroprotective activity.

Quinones (53):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15142R
    Doxorubicin (hydrochloride) (Standard) 25316-40-9 ≥98%
    Doxorubicin (hydrochloride) (Standard) is the analytical standard of Doxorubicin (hydrochloride). This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
    Doxorubicin (hydrochloride) (Standard)
  • HY-N0111R
    Coenzyme Q10 (Standard) 303-98-0 ≥98%
    Coenzyme Q10 (Standard) is the analytical standard of Coenzyme Q10. This product is intended for research and analytical applications. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10 (Standard)
  • HY-B2156R
    Menaquinone-4 (Standard) 863-61-6 ≥98%
    Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
    Menaquinone-4 (Standard)
  • HY-121309R
    Doxorubicinone (Standard) 24385-10-2 ≥98%
    Doxorubicinone (Standard) is the analytical standard of Doxorubicinone. This product is intended for research and analytical applications. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.
    Doxorubicinone (Standard)
  • HY-N0105R
    Rhein (Standard) 478-43-3 ≥98%
    Rhein (Standard) is the analytical standard of Rhein. This product is intended for research and analytical applications.
    Rhein (Standard)
  • HY-N0108R
    Physcion (Standard) 521-61-9 ≥98%
    Physcion (Standard) is the analytical standard of Physcion. This product is intended for research and analytical applications. Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.
    Physcion (Standard)
  • HY-N0886R
    Aloin B (Standard) 28371-16-6 ≥98%
    Aloin B (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an isomer of aloin, a physiologically active anthraquinone compound in aloe.
    Aloin B (Standard)
  • HY-N0366R
    Sennoside B (Standard) 128-57-4 ≥98%
    Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia). Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway.
    Sennoside B (Standard)
  • HY-N2306R
    Aclacinomycin A (Standard) 57576-44-0 ≥98%
    Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis.
    Aclacinomycin A (Standard)
  • HY-N0135R
    Tanshinone IIA (Standard) 568-72-9 ≥98%
    Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2/KDR/Flk-1.
    Tanshinone IIA (Standard)
  • HY-N0360R
    Dihydrotanshinone I (Standard) 87205-99-0 ≥98%
    Dihydrotanshinone I (Standard) is the analytical standard of Dihydrotanshinone I. This product is intended for research and analytical applications. Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.
    Dihydrotanshinone I (Standard)
  • HY-N0563R
    Alizarin (Standard) 72-48-0 ≥98%
    Alizarin (Standard) is the analytical standard of Alizarin. This product is intended for research and analytical applications. Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings.
    Alizarin (Standard)
  • HY-N0822R
    Shikonin (Standard) 517-89-5 ≥98%
    Shikonin (Standard) is the analytical standard of Shikonin. This product is intended for research and analytical applications. Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation.
    Shikonin (Standard)
  • HY-N1972R
    Sennoside C (Standard) 37271-16-2 ≥98%
    Sennoside C (Standard) is the analytical standard of Sennoside C. This product is intended for research and analytical applications. Sennoside C is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).
    Sennoside C (Standard)
  • HY-N1973R
    Sennoside D (Standard) 37271-17-3 ≥98%
    Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).
    Sennoside D (Standard)
  • HY-N2395R
    Chrysophanol 8-O-glucoside (Standard) 13241-28-6 ≥98%
    Chrysophanol 8-O-glucoside (Standard) is the analytical standard of Chrysophanol 8-O-glucoside. This product is intended for research and analytical applications. Chrysophanol 8-O-glucoside, from the roots of Rumex acetosa, shows moderate elastase inhibition activity.
    Chrysophanol 8-O-glucoside (Standard)
  • HY-N6949R
    Juglone (Standard) 481-39-0 ≥98%
    Juglone (Standard) is the analytical standard of Juglone. This product is intended for research and analytical applications. Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
    Juglone (Standard)
  • HY-D0226R
    Quinizarin (Standard) 81-64-1 ≥98%
    Quinizarin (Standard) is the analytical standard of Quinizarin. This product is intended for research and analytical applications. Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.
    Quinizarin (Standard)
  • HY-N0685R
    Pseudohypericin (Standard) 55954-61-5 ≥98%
    Pseudohypericin (Standard) is the analytical standard of Pseudohypericin. This product is intended for research and analytical applications. Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity.
    Pseudohypericin (Standard)
  • HY-N1739R
    Tectoquinone (Standard) 84-54-8 ≥98%
    Tectoquinone (Standard) is the analytical standard of Tectoquinone. This product is intended for research and analytical applications. Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively.
    Tectoquinone (Standard)