Docosatetraenylethanolamide (Synonyms: DEA)

Cat. No.: HY-110016: FAQs
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Docosatetraenylethanolamide (DEA) is a cannabinoid receptor 1 (CB1) agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system.

For research use only. We do not sell to patients.

Docosatetraenylethanolamide Chemical Structure

CAS No. : 150314-35-5

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Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target^[1]

CB1

In Vitro

Docosatetraenylethanolamide inhibits the electrically evoked twitch response of the mouse isolated vas deferens (IC₅₀=95.5 nM).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

375.59

Formula

C₂₄H₄₁NO₂

CAS No.

150314-35-5

SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(NCCO)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hanus L, et al. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J Med Chem. 1993 Oct 1;36(20):3032-4. [Content Brief]

[2]. Pertwee R, et alcts of two endogenous fatty acid ethanolamides on mouse vasa deferentia. Eur J Pharmacol. 1994 Jul 1;259(2):115-20. [Content Brief]

[3]. Walter L, et al. Astrocytes in culture produce anandamide and other acylethanolamides. J Biol Chem. 2002 Jun 7;277(23):20869-76. [Content Brief]

Docosatetraenylethanolamide Related Classifications

Neurological Disease

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Docosatetraenylethanolamide150314-35-5DEAEndogenous MetaboliteCannabinoid Receptorratsynaptosomal membranesnervous systembrainmousevas deferensInhibitorinhibitorinhibit

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