2. GPCR/G Protein
  3. Guanylate Cyclase
  4. A-350619 hydrochloride

A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction.

For research use only. We do not sell to patients.

A-350619 hydrochloride Chemical Structure

A-350619 hydrochloride Chemical Structure

CAS No. : 1217201-17-6

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5 mg USD 165 In-stock
10 mg USD 260 In-stock
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A-350619 hydrochloride Related Antibodies

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Description

A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction[1][2].

IC50 & Target

sGC[1][2].
Molecular Weight

425.41

Formula

C21H26Cl2N2OS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCCCCN(C)C)/C=C/C1=C(SC2=CC=C(C=C2)Cl)C=CC=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (293.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3507 mL 11.7534 mL 23.5067 mL
5 mM 0.4701 mL 2.3507 mL 4.7013 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3507 mL 11.7534 mL 23.5067 mL 58.7668 mL
5 mM 0.4701 mL 2.3507 mL 4.7013 mL 11.7534 mL
10 mM 0.2351 mL 1.1753 mL 2.3507 mL 5.8767 mL
15 mM 0.1567 mL 0.7836 mL 1.5671 mL 3.9178 mL
20 mM 0.1175 mL 0.5877 mL 1.1753 mL 2.9383 mL
25 mM 0.0940 mL 0.4701 mL 0.9403 mL 2.3507 mL
30 mM 0.0784 mL 0.3918 mL 0.7836 mL 1.9589 mL
40 mM 0.0588 mL 0.2938 mL 0.5877 mL 1.4692 mL
50 mM 0.0470 mL 0.2351 mL 0.4701 mL 1.1753 mL
60 mM 0.0392 mL 0.1959 mL 0.3918 mL 0.9794 mL
80 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7346 mL
100 mM 0.0235 mL 0.1175 mL 0.2351 mL 0.5877 mL
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A-350619 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A-3506191217201-17-6A350619A 350619Guanylate Cyclaseerectile dysfunctionInhibitorinhibitorinhibit

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