AA10

Cat. No.: HY-157254: FAQs
Data Sheet Handling Instructions

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AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research.

For research use only. We do not sell to patients.

AA10 Chemical Structure

CAS No. : 2134106-02-6

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Description	AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research^[1].
Molecular Weight	556.65
Formula	C₃₂H₃₆N₄O₅
CAS No.	2134106-02-6
SMILES	O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=CC=C4C=CC=CC4=C3)=O)CC2)=O)CCCCNC(C=C)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Akbar A, et al. Structure-Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase. J Med Chem. 2017 Sep 28;60(18):7910-7927. [Content Brief]

AA10 Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AA102134106-02-6AA 10AA-10GlutaminaseTG2 inhibitorInhibitorinhibitorinhibit

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AA10

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