2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. Cannabinoid Receptor Potassium Channel
  4. AB-FUBICA

AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms.

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AB-FUBICA Chemical Structure

AB-FUBICA Chemical Structure

CAS No. : 1801338-22-6

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AB-FUBICA Related Antibodies

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Description

AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms[1].

IC50 & Target

CB1

21 nM (EC50)

CB2

15 nM (EC50)

Molecular Weight

367.42

Formula

C21H22FN3O2
CAS No.
SMILES

CC(C)[C@@H](C(N)=O)NC(C1=CN(CC2=CC=C(C=C2)F)C3=CC=CC=C13)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AB-FUBICA Related Classifications

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AB-FUBICA1801338-22-6Cannabinoid ReceptorPotassium ChannelKcsAInhibitorinhibitorinhibit

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