2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. ABP 215

ABP 215 (Bevacizumab-awwb), a Bevacizumab (Bevacizumab (HY-P9906)) biosimilar, is a humanized IgG1 monoclonal antibody targeting VEGFA (VEGFR). ABP 215 has anticancer effects, and can be used metastatic colorectal cancer (mCRC) research.

For research use only. We do not sell to patients.

ABP 215 Chemical Structure

ABP 215 Chemical Structure

CAS No. : 1438851-35-4

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ABP 215 Related Antibodies

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Description

ABP 215 (Bevacizumab-awwb), a Bevacizumab (Bevacizumab (HY-P9906)) biosimilar, is a humanized IgG1 monoclonal antibody targeting VEGFA (VEGFR). ABP 215 has anticancer effects, and can be used metastatic colorectal cancer (mCRC) research[1][2].

In Vitro

ABP 215 (Bevacizumab-awwb) binds to VEGF-A and prevents the binding of VEGF-A to VEGF receptors on the surface of endothelial cells, inhibiting endothelial cell proliferation and new blood vessel formation, thereby leading to normalization of the tumor vasculature[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ABP 215 Related Antibodies
Clinical Trial
CAS No.
SMILES

[ABP 215]
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ABP 215 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ABP 2151438851-35-4ABP215ABP-215VEGFRVascular endothelial growth factor receptorVEGFAmetastatic colorectal cancerBevacizumab biosimilaranticancer effectInhibitorinhibitorinhibit

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