ABT-702 hydrochloride (Synonyms: Adenosine Kinase Inhibitor hydrochloride)

Cat. No.: HY-112482A: FAQs
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ABT-702 hydrochloride is a potent inhibitor of adenosine kinase with an IC₅₀ of 1.7 nM.

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ABT-702 hydrochloride Chemical Structure

CAS No. : 2624336-92-9

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Other In-stock Forms of ABT-702 hydrochloride:

ABT-702 dihydrochloride

Other Forms of ABT-702 hydrochloride:

ABT-702 dihydrochloride In-stock

1 Publications Citing Use of MCE ABT-702 hydrochloride

•Cell Death Discov. 2023 Jul 26;9(1):262. [Abstract]

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Description	ABT-702 hydrochloride is a potent inhibitor of adenosine kinase with an IC₅₀ of 1.7 nM^[1]^[2].
Molecular Weight	499.79
Formula	C₂₂H₂₀BrClN₆O
CAS No.	2624336-92-9
SMILES	NC1=C(C(C2=CC=CC(Br)=C2)=CC(C3=CC=C(N4CCOCC4)N=C3)=N5)C5=NC=N1.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Jarvis MF, et al. ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse. J Pharmacol Exp Ther. 2000 Dec;295(3):1156-64. [Content Brief] [2]. Parkinson FE, et al. The Effect of Endogenous Adenosine on Neuronal Activity in Rats: An FDG PET Study. J Neuroimaging. 2016 Jul;26(4):403-5. [Content Brief]

ABT-702 hydrochloride Related Classifications

Inflammation/Immunology

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ABT-7022624336-92-9Adenosine Kinase InhibitorABT702ABT 702Adenosine KinaseADKinflammationadenosine kinaseInhibitorinhibitorinhibit

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ABT-702 hydrochloride (Synonyms: Adenosine Kinase Inhibitor hydrochloride)

Other Forms of ABT-702 hydrochloride:

ABT-702 hydrochloride Related Antibodies

1 Publications Citing Use of MCE ABT-702 hydrochloride

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review