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  2. Isotope-Labeled Compounds Carbonic Anhydrase Autophagy
  3. Acetazolamide-13C2,d3

Acetazolamide-13C2,d3 is the 13C- and deuterium labeled Acetazolamide. Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX[1]. Diuretic effects[4].

For research use only. We do not sell to patients.

Acetazolamide-<sup>13</sup>C<sub>2</sub>,d<sub>3</sub> Chemical Structure

Acetazolamide-13C2,d3 Chemical Structure

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Description

Acetazolamide-13C2,d3 is the 13C- and deuterium labeled Acetazolamide. Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX[1]. Diuretic effects[4].

IC50 & Target

CA Ⅸ

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[37].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

227.25

Formula

C213C2H3D3N4O3S2

Unlabeled CAS

59-66-5

SMILES

O=[13C](NC1=NN=C(S(=O)(N)=O)S1)[13C]([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Acetazolamide-13C2,d3
Cat. No.:
HY-B0782S1
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