1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Acetyl-L-carnitine-d3-1 hydrochloride

Acetyl-L-carnitine-d3-1 hydrochloride  (Synonyms: O-Acetyl-L-carnitine-d3-1 (hydrochloride))

Cat. No.: HY-B0762S1 Purity: 98.5%
COA Handling Instructions

Acetyl-L-carnitine-d3-1 (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

For research use only. We do not sell to patients.

Acetyl-L-carnitine-d<sub>3</sub>-1 hydrochloride Chemical Structure

Acetyl-L-carnitine-d3-1 hydrochloride Chemical Structure

CAS No. : 362049-62-5

Size Price Stock Quantity
5 mg USD 120 In-stock
10 mg USD 190 In-stock
25 mg USD 440 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Acetyl-L-carnitine-d3-1 hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Acetyl-L-carnitine-d3-1 (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

242.72

Formula

C9H15D3ClNO4

CAS No.
Unlabeled CAS

5080-50-2

Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)C[C@H](OC(C([2H])([2H])[2H])=O)CC(O)=O.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1029.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1200 mL 20.5999 mL 41.1997 mL
5 mM 0.8240 mL 4.1200 mL 8.2399 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (412.00 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.5%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.1200 mL 20.5999 mL 41.1997 mL 102.9993 mL
5 mM 0.8240 mL 4.1200 mL 8.2399 mL 20.5999 mL
10 mM 0.4120 mL 2.0600 mL 4.1200 mL 10.2999 mL
15 mM 0.2747 mL 1.3733 mL 2.7466 mL 6.8666 mL
20 mM 0.2060 mL 1.0300 mL 2.0600 mL 5.1500 mL
25 mM 0.1648 mL 0.8240 mL 1.6480 mL 4.1200 mL
30 mM 0.1373 mL 0.6867 mL 1.3733 mL 3.4333 mL
40 mM 0.1030 mL 0.5150 mL 1.0300 mL 2.5750 mL
50 mM 0.0824 mL 0.4120 mL 0.8240 mL 2.0600 mL
60 mM 0.0687 mL 0.3433 mL 0.6867 mL 1.7167 mL
80 mM 0.0515 mL 0.2575 mL 0.5150 mL 1.2875 mL
100 mM 0.0412 mL 0.2060 mL 0.4120 mL 1.0300 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Product Name:
Acetyl-L-carnitine-d3-1 hydrochloride
Cat. No.:
HY-B0762S1
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