1. Membrane Transporter/Ion Channel Others Metabolic Enzyme/Protease Neuronal Signaling
  2. nAChR Calcium Channel Endogenous Metabolite Isotope-Labeled Compounds
  3. Acetylcholine-d16 bromide

Acetylcholine-d16 bromide  (Synonyms: ACh-d16 bromide)

Cat. No.: HY-B0282AS3 Purity: ≥98.0%
COA Handling Instructions

Acetylcholine-d16 (bromide) is the deuterium labeled Acetylcholine bromide[1].

For research use only. We do not sell to patients.

Acetylcholine-d<sub>16</sub> bromide Chemical Structure

Acetylcholine-d16 bromide Chemical Structure

CAS No. : 347841-43-4

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1 mg USD 130 In-stock
5 mg USD 440 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Acetylcholine-d16 bromide:

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  • Biological Activity

  • Purity & Documentation

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Description

Acetylcholine-d16 (bromide) is the deuterium labeled Acetylcholine bromide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

242.21

Formula

C7D16BrNO2

CAS No.
Unlabeled CAS

66-23-9

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C(OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1032.16 mM; Need ultrasonic)

H2O : 250 mg/mL (1032.16 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1286 mL 20.6432 mL 41.2865 mL
5 mM 0.8257 mL 4.1286 mL 8.2573 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 4.1286 mL 20.6432 mL 41.2865 mL 103.2162 mL
5 mM 0.8257 mL 4.1286 mL 8.2573 mL 20.6432 mL
10 mM 0.4129 mL 2.0643 mL 4.1286 mL 10.3216 mL
15 mM 0.2752 mL 1.3762 mL 2.7524 mL 6.8811 mL
20 mM 0.2064 mL 1.0322 mL 2.0643 mL 5.1608 mL
25 mM 0.1651 mL 0.8257 mL 1.6515 mL 4.1286 mL
30 mM 0.1376 mL 0.6881 mL 1.3762 mL 3.4405 mL
40 mM 0.1032 mL 0.5161 mL 1.0322 mL 2.5804 mL
50 mM 0.0826 mL 0.4129 mL 0.8257 mL 2.0643 mL
60 mM 0.0688 mL 0.3441 mL 0.6881 mL 1.7203 mL
80 mM 0.0516 mL 0.2580 mL 0.5161 mL 1.2902 mL
100 mM 0.0413 mL 0.2064 mL 0.4129 mL 1.0322 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Acetylcholine-d16 bromide
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