1. Membrane Transporter/Ion Channel Others Metabolic Enzyme/Protease Neuronal Signaling
  2. nAChR Calcium Channel Endogenous Metabolite Isotope-Labeled Compounds
  3. Acetylcholine-d4 bromide

Acetylcholine-d4 bromide  (Synonyms: ACh-d4 bromide)

Cat. No.: HY-B0282AS1 Purity: ≥98.0%
SDS COA Handling Instructions Technical Support

Acetylcholine-d4 (bromide) is the deuterium labeled Acetylcholine bromide[1].

For research use only. We do not sell to patients.

Acetylcholine-d<sub>4</sub> bromide Chemical Structure

Acetylcholine-d4 bromide Chemical Structure

CAS No. : 93449-31-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Acetylcholine-d4 bromide:

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Description

Acetylcholine-d4 (bromide) is the deuterium labeled Acetylcholine bromide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

230.14

Formula

C7H12D4BrNO2

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])(OC(C)=O)C([N+](C)(C)C)([2H])[2H].[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1086.30 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3452 mL 21.7259 mL 43.4518 mL
5 mM 0.8690 mL 4.3452 mL 8.6904 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.3452 mL 21.7259 mL 43.4518 mL 108.6295 mL
5 mM 0.8690 mL 4.3452 mL 8.6904 mL 21.7259 mL
10 mM 0.4345 mL 2.1726 mL 4.3452 mL 10.8630 mL
15 mM 0.2897 mL 1.4484 mL 2.8968 mL 7.2420 mL
20 mM 0.2173 mL 1.0863 mL 2.1726 mL 5.4315 mL
25 mM 0.1738 mL 0.8690 mL 1.7381 mL 4.3452 mL
30 mM 0.1448 mL 0.7242 mL 1.4484 mL 3.6210 mL
40 mM 0.1086 mL 0.5431 mL 1.0863 mL 2.7157 mL
50 mM 0.0869 mL 0.4345 mL 0.8690 mL 2.1726 mL
60 mM 0.0724 mL 0.3621 mL 0.7242 mL 1.8105 mL
80 mM 0.0543 mL 0.2716 mL 0.5431 mL 1.3579 mL
100 mM 0.0435 mL 0.2173 mL 0.4345 mL 1.0863 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Acetylcholine-d4 bromide
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