1. MAPK/ERK Pathway PI3K/Akt/mTOR Apoptosis Autophagy NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  2. JNK Akt Apoptosis Autophagy Reactive Oxygen Species
  3. Actein (Standard)

Actein (Standard) is the analytical standard of Actein. This product is intended for research and analytical applications. Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo.

For research use only. We do not sell to patients.

Actein (Standard) Chemical Structure

Actein (Standard) Chemical Structure

CAS No. : 18642-44-9

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Description
Molecular Weight

676.83

Formula

C37H56O11

CAS No.
SMILES

C[C@]12[C@@]3([H])[C@@]4(C[C@@H](OC(C)=O)[C@@]1([C@]5([H])[C@](O[C@]6([C@H]7[C@]([C@@H](O)O6)(C)O7)C[C@H]5C)([H])C2)C)[C@@]8([C@@](C(C)([C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)CC8)C)([H])CC3)C4

Structure Classification
Initial Source
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Actein (Standard)
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HY-N6872R
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