1. Others
  2. Others
  3. Adam-20-S

Adam-20-S is a potent glucosinolate sulfatase inhibitor with an IC50 value of 9.04 μg/mL. Adam-20-S impaires glucosinolate metabolism to produce more toxic isothiocyanates in P. xylostella.

For research use only. We do not sell to patients.

Adam-20-S Chemical Structure

Adam-20-S Chemical Structure

CAS No. : 2413880-52-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Adam-20-S is a potent glucosinolate sulfatase inhibitor with an IC50 value of 9.04 μg/mL. Adam-20-S impaires glucosinolate metabolism to produce more toxic isothiocyanates in P. xylostella[1].

IC50 & Target

IC50:9.04 μg/mL[1]

Cellular Effect
Cell Line Type Value Description References
JEG-3 IC50
67.7 nM
Compound: 1p
Inhibition of steroid sulfatase in human JEG3 cell lysates using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysis
Inhibition of steroid sulfatase in human JEG3 cell lysates using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysis
[PMID: 32173116]
T47D IC50
3.4 μM
Compound: 1p
Antiproliferative activity against human T47D cells assessed as reduction in cell proliferation measured after 5 days in presence of estradiol sulfate by crystal violet staining based assay
Antiproliferative activity against human T47D cells assessed as reduction in cell proliferation measured after 5 days in presence of estradiol sulfate by crystal violet staining based assay
[PMID: 32173116]
Molecular Weight

368.42

Formula

C17H21FN2O4S

CAS No.
SMILES

FC1=CC(C(NC2(C3)CC4CC3CC(C2)C4)=O)=CC=C1OS(N)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Adam-20-S Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Adam-20-S
Cat. No.:
HY-156407
Quantity:
MCE Japan Authorized Agent: