1. Metabolic Enzyme/Protease
  2. ADAMTS
  3. Adamtsostatin 18

Adamtsostatin 18 is an anti-angiogenic peptide derived from proteins containing type I thrombospondin motifs. Adamtsostatin 18 inhibits cell migration and proliferation.

For research use only. We do not sell to patients.

Adamtsostatin 18 Chemical Structure

Adamtsostatin 18 Chemical Structure

CAS No. : 929554-95-0

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Description

Adamtsostatin 18 is an anti-angiogenic peptide derived from proteins containing type I thrombospondin motifs. Adamtsostatin 18 inhibits cell migration and proliferation[1].

In Vitro

Adamtsostatin 18 ( 0.01, 0.1, 1, 10, 20, 30, 40 µg/mL; 3 days) inhibits cell proliferation in HUVECs[1].
Adamtsostatin 18 (10, 30 µg/mL; 20 h) inhibits the migration of the endothelial cells in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: HUVECs
Concentration: 0.01, 0.1, 1, 10, 20, 30, 40 µg/mL
Incubation Time: 3 days
Result: Inhibitted the cell proliferation.
Molecular Weight

2145.38

Formula

C89H141N29O29S2

CAS No.
Sequence Shortening

SKWSECSRTCGGGVKFQER

SMILES

OC[C@H](N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CS)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(NCC(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Adamtsostatin 18
Cat. No.:
HY-P4002
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