Adenosine-5′-monophosphate-¹⁵N₅ sodium 

Adenosine-5′-monophosphate-¹⁵N₅ (sodium) is the ¹⁵N labeled Adenosine-5′-monophosphate sodium[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

396.15

C₁₀H₁₂¹⁵N₅Na₂O₇P

Solid

White to off-white

[15NH2]C1=[15N]C=[15N]C2=C1[15N]=C[15N]2[C@@]3(O[C@@H]([C@@]([H])([C@@]3([H])O)O)COP(O[Na])(O[Na])=O)[H]

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]