1. GPCR/G Protein Neuronal Signaling
  2. CGRP Receptor
  3. Adrenotensin (human)

Adrenotensin (human)  (Synonyms: Pro-ADM-153-185 (human))

Cat. No.: HY-P3919
Handling Instructions

Adrenotensin (human) (Pro-ADM-153-185 (human)) is a 153-185 fragment of precursor peptide of Adrenomedullin. Adrenomedullin (ADM) is a 52-amino acid multifunctional peptide, which belongs to the CGRP superfamily of vasoactive peptide hormones.

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Adrenotensin (human) Chemical Structure

Adrenotensin (human) Chemical Structure

CAS No. : 166546-72-1

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Description

Adrenotensin (human) (Pro-ADM-153-185 (human)) is a 153-185 fragment of precursor peptide of Adrenomedullin. Adrenomedullin (ADM) is a 52-amino acid multifunctional peptide, which belongs to the CGRP superfamily of vasoactive peptide hormones[1].

In Vitro

The human Adrenomedullin (ADM) peptide is encoded by a single gene, which is located on chromosome 11 and consists of four exons and three introns. Translation of the transcript generates the 185 amino acid precursor peptide prepro-ADM, which is subsequently converted into the 164 amino acid pro-ADM by cleavage of the N-terminal signal-peptide. Pro-ADM is further processed into proADM N-terminal 20 peptide (PAMP), midregional pro-ADM, Adrenotensin Pro-ADM-153-185 and immature ADM, a C-terminally glycine-extended version of ADM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3219.56

Formula

C143H224N42O43

CAS No.
Sequence Shortening

SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Adrenotensin (human)
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