2. Stem Cell/Wnt TGF-beta/Smad
  3. RUNX
  4. AI-4-57

AI-4-57 is an allosteric inhibitor for CBFβ SMMHC-RUNX1 (core binding factor β and the smooth-muscle myosin heavy chain) interaction with an IC50 of 22 μM.

For research use only. We do not sell to patients.

AI-4-57 Chemical Structure

AI-4-57 Chemical Structure

CAS No. : 63053-14-5

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Based on 1 publication(s) in Google Scholar

AI-4-57 Related Antibodies

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RUNX2

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Description

AI-4-57 is an allosteric inhibitor for CBFβ SMMHC-RUNX1 (core binding factor β and the smooth-muscle myosin heavy chain) interaction with an IC50 of 22 μM[1].

Molecular Weight

225.25

Formula

C13H11N3O
CAS No.
SMILES

COC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AI-4-57 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AI-4-5763053-14-5RUNXRunt-related transcription factorsleukemiaallostericInhibitorinhibitorinhibit

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