2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. AICA-riboside, 5′-phosphate

AICA-riboside, 5′-phosphate  (Synonyms: AICAR-5'-MP)

Cat. No.: HY-134356 Purity: 99.95%
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AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. .

For research use only. We do not sell to patients.

AICA-riboside, 5′-phosphate Chemical Structure

AICA-riboside, 5′-phosphate Chemical Structure

CAS No. : 3031-94-5

Size Price Stock Quantity
1 mg USD 110 In-stock
5 mg USD 230 In-stock
10 mg USD 368 In-stock
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Based on 1 publication(s) in Google Scholar

AICA-riboside, 5′-phosphate Related Antibodies

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Description

AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. [1].
Cellular Effect
Cell Line Type Value Description References
DU-145 IC50
59 μM
Compound: AICAR
Cytotoxicity against DU145 cells after 72 hrs
Cytotoxicity against DU145 cells after 72 hrs
[PMID: 17181154]
HeLa IC50
126 μM
Compound: AICAR
Cytotoxicity against HeLa cells after 72 hrs
Cytotoxicity against HeLa cells after 72 hrs
[PMID: 17181154]
Molecular Weight

338.21

Formula

C9H15N4O8P
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

O[C@@H]1[C@@H](COP(O)(O)=O)O[C@@H](N2C(N)=C(C(N)=O)N=C2)[C@@H]1O
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 4.9 mg/mL (14.49 mM; ultrasonic and warming and adjust pH to 6 with NaOH and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9567 mL 14.7837 mL 29.5674 mL
5 mM 0.5913 mL 2.9567 mL 5.9135 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.9567 mL 14.7837 mL 29.5674 mL 73.9186 mL
5 mM 0.5913 mL 2.9567 mL 5.9135 mL 14.7837 mL
10 mM 0.2957 mL 1.4784 mL 2.9567 mL 7.3919 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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AICA-riboside, 5′-phosphate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AICA-riboside, 5′-phosphate3031-94-5AICAR-5'-MPEndogenous MetaboliteanalogueInhibitorinhibitorinhibit

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