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  5. Ajugasterone C

Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats.

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Ajugasterone C Chemical Structure

Ajugasterone C Chemical Structure

CAS No. : 23044-80-6

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Description

Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats[1][2].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
> 700 μM
Compound: 3
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
[PMID: 26988299]
Huh-7 EC50
10.05 μM
Compound: 3
Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
12.15 μM
Compound: 3
Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
15.7 μM
Compound: 3
Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Huh-7 EC50
9.48 μM
Compound: 3
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
[PMID: 26988299]
Molecular Weight

480.63

Formula

C27H44O7

CAS No.
SMILES

O[C@]([C@@]1(C[C@H]2O)C)(CC[C@]1([H])[C@@](C)(O)[C@H](O)CCC(C)C)C([C@@]2([H])[C@@]3([C@@]4([H])C[C@@H](O)[C@@H](O)C3)C)=CC4=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ajugasterone C
Cat. No.:
HY-N2196
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