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  3. AKR1C3-IN-7

AKR1C3-IN-7 (Compound 13) is a potent, selective AKR1C3 inhibitor with an IC50 of 0.19 μM. AKR1C3-IN-7 shows antitumor activity.

For research use only. We do not sell to patients.

AKR1C3-IN-7 Chemical Structure

AKR1C3-IN-7 Chemical Structure

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Description

AKR1C3-IN-7 (Compound 13) is a potent, selective AKR1C3 inhibitor with an IC50 of 0.19 μM. AKR1C3-IN-7 shows antitumor activity[1].

IC50 & Target

IC50: 0.19 μM (AKR1C3)[1]

In Vitro

AKR1C3-IN-7 (Compound 13) shows antiproliferative activity with an IC50 of 54.81 ± 2.47 μM against prostate cancer cell line 22rv1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

400.43

Formula

C24H20N2O4

SMILES

COC1=CC=C(C=C1)CC2=C(C(O)=NO2)C(NC3=CC(C4=CC=CC=C4)=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AKR1C3-IN-7
Cat. No.:
HY-146574
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