2. PI3K/Akt/mTOR
  3. Akt
  4. AKT-IN-13

AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer.

For research use only. We do not sell to patients.

AKT-IN-13 Chemical Structure

AKT-IN-13 Chemical Structure

CAS No. : 2459489-51-9

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AKT-IN-13 Related Antibodies

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Description

AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].

IC50 & Target[1]

Akt1

1.6 nM (IC50)

Akt2

2.4 nM (IC50)

Akt3

0.3 nM (IC50)

In Vitro

AKT-IN-13 (compound 4b) displays good potency in the LNCap cell line with an IC50 value of 103 nM and a high free fraction with 51.3% human plasma protein binding (PPB)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AKT-IN-13 Related Antibodies
Molecular Weight

470.99

Formula

C24H31ClN6O2
CAS No.
SMILES

O=C(N1CCN(CC1)C2=C3C(NC(C[C@H]3C)=O)=NC=N2)[C@@H](C4=CC=C(C=C4)Cl)CNC(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AKT-IN-13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKT-IN-132459489-51-9AktPKBProtein kinase BanticancerLNCapInhibitorinhibitorinhibit

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