2. GPCR/G Protein
  3. Endothelin Receptor
  4. [Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA)

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) 

Cat. No.: HY-P1019A
Handling Instructions

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[Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) Chemical Structure

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) Chemical Structure

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Other Forms of [Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA):

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) Related Antibodies

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ETA ETB

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Description

[Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction[1].

IC50 & Target[1]

ETB

 

In Vitro

[Ala1,3,11,15]-Endothelin (53-63) (TFA) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) Related Antibodies
Molecular Weight

2481.70

Formula

C111H164F3N25O34S
Sequence

Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Sequence Shortening

ASASSLMDKEAVYFAHLDIIW
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA)Endothelin ReceptorlinearpeptideendothelinET-1BETBInhibitorinhibitorinhibit

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