Alamethicin F 50 

Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent^[1][2].

1963.32

C₉₂H₁₅₁N₂₃O₂₄

56165-93-6

Ac-{Aib}-Pro-{Aib}-Ala-{Aib}-Ala-Gln-{Aib}-Val-{Aib}-Gly-Leu-{Aib}-Pro-Val-{Aib}-{Aib}-QQ-{L-Phenylalaninol}

Ac-{Aib}-P-{Aib}-A-{Aib}-AQ-{Aib}-V-{Aib}-GL-{Aib}-PV-{Aib}-{Aib}-QQ-{L-Phenylalaninol}

O=C([C@H]1N(CCC1)C(C(C)(C)NC(C)=O)=O)NC(C)(C)C(N[C@@H](C)C(NC(C)(C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(NC(C)(C)C(N[C@@H](C(C)C)C(NC(C)(C)C(NCC(N[C@@H](CC(C)C)C(NC(C)(C)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(NC(C)(C)C(NC(C)(C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](CO)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Meyer CE, et al., A polypeptide antibacterial agent isolated from Trichoderma viride. Experientia. 1967 Feb 15;23(2):85-6.  [Content Brief]

  [2]. Kirschbaum J, et al., Sequences of alamethicins F30 and F50 reconsidered and reconciled. J Pept Sci. 2003 Nov-Dec;9(11-12):799-809.  [Content Brief]