2. Anti-infection
  3. Fungal
  4. Albaconazole

Albaconazole (UR 9825) is a broad-spectrum triazole and oral activity antifungal agent.

For research use only. We do not sell to patients.

Albaconazole Chemical Structure

Albaconazole Chemical Structure

CAS No. : 187949-02-6

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Based on 1 publication(s) in Google Scholar

Other Forms of Albaconazole:

Albaconazole Related Antibodies

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Description

Albaconazole (UR 9825) is a broad-spectrum triazole and oral activity antifungal agent[1][2].

Cellular Effect
Cell Line Type Value Description References
CHO IC50
34.86 μM
Compound: 7
Inhibition of human ERG expressed in CHO cells by whole-cell patch clamp assay
Inhibition of human ERG expressed in CHO cells by whole-cell patch clamp assay
[PMID: 24564525]
In Vitro

Albaconazole (UR 9825) shows antifungal activity with MIC50s of ≤0.0002, ≤0.0002, ≤0.0002, 0.06, 0.015, ≤0.0002 mg/L for C. albicans, C. parapsilosis,C. tropicalis, C. glabrata, C. krusei, C. guilliermondii, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Albaconazole Related Antibodies
In Vivo

Albaconazole (15, 25, 50 mg/kg; p.o.; once daily for 10 days) shows antifungal activity in scedosporium prolificans infection in rabbits[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 2.5 kg New Zealand White male rabbits[2]
Dosage: 15, 25, 50 mg/kg
Administration: P.o.; once daily for 10 days
Result: Showed lower tissue burdens than the control group.S. prolificans was undetectable in the liver, spleen, and lung cultures, attenuated the histopathological severity in the kidney.
Molecular Weight

431.82

Formula

C20H16ClF2N5O2
CAS No.
SMILES

C[C@@H](N1C(C2=CC=C(Cl)C=C2N=C1)=O)[C@@](O)(C3=C(C=C(C=C3)F)F)CN4C=NC=N4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Albaconazole Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Albaconazole187949-02-6UR 9825UR9825UR-9825Fungalscedosporium prorificansoral activityInhibitorinhibitorinhibit

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