Albomycin

Cat. No.: HY-142072: FAQs
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Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer.

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Albomycin Chemical Structure

CAS No. : 1414-39-7

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Description	Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer^[1].
In Vitro	Albomycin also binds to FhuA, competing with ferrichrome, FhuA is a β-strand barrel buried in the outer membrane of E.coli. Otherwise, Albomycin binds to FhuD, a periplasmic subunit of the inner membrane ABC transporter FhuB/FhuC^[1]. Albomycin remarkably inhibits the growth of Streptococcus pneumonia strains with minimal inhibitory concentrations (MIC) of 4-62 nM^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Albomycin Related Antibodies
CAS No.	1414-39-7
SMILES	[ALBOMYCIN]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Travin DY, et al. Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases. RSC Chem Biol. 2021 Feb 22;2(2):468-485. [Content Brief]

Albomycin Related Classifications

Infection

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Albomycin1414-39-7AntibioticDNA/RNA SynthesisBacterialInhibitorinhibitorinhibit

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