2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Aldicarb sulfoxide

Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish.

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Aldicarb sulfoxide Chemical Structure

Aldicarb sulfoxide Chemical Structure

CAS No. : 1646-87-3

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Aldicarb sulfoxide Related Antibodies

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Description

Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish[1][2].

IC50 & Target

IC50: 10 μM (zebrafish ChE); IC50: 10 μM (zebrafish CaE)[2]
In Vitro

Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%[1].
Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aldicarb sulfoxide Related Antibodies
Molecular Weight

206.26

Formula

C7H14N2O3S
CAS No.
SMILES

CC(C)(/C=N/OC(NC)=O)S(C)=O
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aldicarb sulfoxide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aldicarb sulfoxide1646-87-3Drug MetabolitemetaboliteAldicarbglutathionezebrafishCHO-K1Inhibitorinhibitorinhibit

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