2. TGF-beta/Smad
  3. TGF-β Receptor
  4. ALK5-IN-80

ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC50 value of 3.7 nM. ALK5-IN-80 can be used for cancer research.

For research use only. We do not sell to patients.

ALK5-IN-80 Chemical Structure

ALK5-IN-80 Chemical Structure

CAS No. : 3039952-63-8

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ALK5-IN-80 Related Antibodies

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ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

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Description

ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC50 value of 3.7 nM. ALK5-IN-80 can be used for cancer research[1].

IC50 & Target

IC50: 3.7 nM (ALK5), 73.7 nM (ALK1), 183 nM (ALK2), >10000 nM (ALK3), 3690 nM (ALK4), >10000 nM (ALK6), 6344 nM (ACTR2B)[1]
Molecular Weight

451.48

Formula

C21H18FN7O2S
CAS No.
SMILES

O=C(N)C1=C(C2=CC(C(C)=O)=CN2)SC(N(C3CC3)C4=CN(N=C4)C5=C(F)C=NC=C5)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ALK5-IN-80 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALK5-IN-803039952-63-8TGF-β ReceptorTransforming growth factor beta receptorsALK5 inhibitorTGF-βInhibitorinhibitorinhibit

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