2. Cell Cycle/DNA Damage
  3. DNA Alkylator/Crosslinker
  4. Altretamine hydrochloride

Altretamine hydrochloride  (Synonyms: ENT-50852 hydrochloride; RB-1515 hydrochloride; WR-95704 hydrochloride)

Cat. No.: HY-B0181A
Handling Instructions Technical Support

Altretamine hydrochloride is an alkylating antineoplastic agent.

For research use only. We do not sell to patients.

Altretamine hydrochloride Chemical Structure

Altretamine hydrochloride Chemical Structure

CAS No. : 2975-00-0

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Altretamine hydrochloride Related Antibodies

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Description

Altretamine hydrochloride is an alkylating antineoplastic agent.

In Vitro

Altretamine hydrochloride is an antineoplastic agent[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Altretamine hydrochloride Related Antibodies
In Vivo

Altretamine (100, 133 mg/kg, ip.) in combination with Irofulven, increases the antitumor effect in mice bearing MV522 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

246.74

Formula

C9H19ClN6
CAS No.
SMILES

CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Animal Administration
[1]

Mice[1]
Balb/c nu/nu 4 week old female mice weighing 18-22 g, receive s.c. injections of 8-10 million MV522 cells. Altretamine is administered i.p. three times a week for 3 weeks, starting on day 10 after tumor implantation. Tumor size is measured in two perpendicular diameters and tumor weight (TW) estimated according to the formula: w = [(width)2 × length/2]. Altretamine is prepared as stock solutions of 1-10 mg/mL in 40% DMSO/normal saline and diluted with 10% DMSO/normal saline as required[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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Altretamine hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Altretamine2975-00-0ENT-50852RB-1515WR-95704ENT50852ENT 50852RB1515RB 1515WR95704WR 95704DNA Alkylator/CrosslinkerInhibitorinhibitorinhibit

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