2. Cell Cycle/DNA Damage
  3. DNA Alkylator/Crosslinker
  4. Altretamine hydrochloride

Altretamine hydrochloride  (Synonyms: ENT-50852 hydrochloride; RB-1515 hydrochloride; WR-95704 hydrochloride)

Cat. No.: HY-B0181A
Handling Instructions

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Altretamine hydrochloride is an alkylating antineoplastic agent.

For research use only. We do not sell to patients.

Altretamine hydrochloride Chemical Structure

Altretamine hydrochloride Chemical Structure

CAS No. : 2975-00-0

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Altretamine hydrochloride Related Antibodies

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Description

Altretamine hydrochloride is an alkylating antineoplastic agent.

In Vitro

Altretamine hydrochloride is an antineoplastic agent[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Altretamine hydrochloride Related Antibodies
In Vivo

Altretamine (100, 133 mg/kg, ip.) in combination with Irofulven, increases the antitumor effect in mice bearing MV522 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

246.74

Formula

C9H19ClN6
CAS No.
SMILES

CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Animal Administration
[1]

Mice[1]
Balb/c nu/nu 4 week old female mice weighing 18-22 g, receive s.c. injections of 8-10 million MV522 cells. Altretamine is administered i.p. three times a week for 3 weeks, starting on day 10 after tumor implantation. Tumor size is measured in two perpendicular diameters and tumor weight (TW) estimated according to the formula: w = [(width)2 × length/2]. Altretamine is prepared as stock solutions of 1-10 mg/mL in 40% DMSO/normal saline and diluted with 10% DMSO/normal saline as required[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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Altretamine hydrochloride Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Altretamine2975-00-0ENT-50852RB-1515WR-95704ENT50852ENT 50852RB1515RB 1515WR95704WR 95704DNA Alkylator/CrosslinkerInhibitorinhibitorinhibit

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