AM-9022

Cat. No.: HY-162110: FAQs
Data Sheet Handling Instructions

Molarity Calculator

AM-9022 is an orally active, potent, selective KIF18A inhibitor that can be used for research on cancer.

For research use only. We do not sell to patients.

AM-9022 Chemical Structure

CAS No. : 2446872-46-2

Size	Price	Stock
1 mg	USD 550	Ask For Quote & Lead Time
5 mg	USD 1250	Ask For Quote & Lead Time
10 mg	USD 2000	Ask For Quote & Lead Time
25 mg	USD 4000	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description	AM-9022 is an orally active, potent, selective KIF18A inhibitor that can be used for research on cancer^[1].
Molecular Weight	578.67
Formula	C₂₇H₃₆F₂N₆O₄S
CAS No.	2446872-46-2
SMILES	O=C(C1=CC=C(NS([C@H](C)CO)(=O)=O)C=C1N2CCC3(CC3)CC2)NC4=CC(C)=NC(N5CCC(F)(F)CC5)=N4
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Payton M, et al. Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer. 2023 Dec 27. [Content Brief]

AM-9022 Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AM-90222446872-46-2AM9022AM 9022Microtubule/TubulinKIF18A inhibitorcancermitoticchromosomal instabilityorally activeInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

AM-9022

AM-9022 Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review