1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. Amidepsine A

Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity.

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Amidepsine A Chemical Structure

Amidepsine A Chemical Structure

CAS No. : 169181-28-6

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1 mg USD 626 In-stock

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Description

Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].

Molecular Weight

567.54

Formula

C29H29NO11

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC1=CC(C)=C(C(OC2=CC(C)=C(C(NC(C(O)=O)C)=O)C(O)=C2)=O)C(O)=C1)C3=C(C)C=C(OC)C=C3OC

Structure Classification
Initial Source

Humicola sp. FO-2942

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5.79 mg/mL (10.20 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7620 mL 8.8100 mL 17.6199 mL
5 mM 0.3524 mL 1.7620 mL 3.5240 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7620 mL 8.8100 mL 17.6199 mL 44.0498 mL
5 mM 0.3524 mL 1.7620 mL 3.5240 mL 8.8100 mL
10 mM 0.1762 mL 0.8810 mL 1.7620 mL 4.4050 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Amidepsine A
Cat. No.:
HY-125319
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