2. PROTAC
  3. PROTAC Linkers
  4. Amine-PEG3-Desthiobiotin

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Amine-PEG3-Desthiobiotin Chemical Structure

Amine-PEG3-Desthiobiotin Chemical Structure

CAS No. : 2237234-71-6

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Based on 1 publication(s) in Google Scholar

Amine-PEG3-Desthiobiotin Related Antibodies

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Description

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Amine-PEG3-Desthiobiotin Related Antibodies
Molecular Weight

388.50

Formula

C18H36N4O5
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(NCCOCCOCCOCCN)CCCCC[C@H]([C@H](C)N1)NC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Amine-PEG3-Desthiobiotin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amine-PEG3-Desthiobiotin2237234-71-6PROTAC LinkersInhibitorinhibitorinhibit

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Product Name:
Amine-PEG3-Desthiobiotin
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