Amoxicillin-¹³C₆  (Synonyms: Amoxycillin-¹³C₆)

Amoxicillin-¹³C₆ is the ¹³C₆ labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

371.36

C₁₀¹³C₆H₁₉N₃O₅S

26787-78-0

OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H]([13C]3=[13CH][13CH]=[13C](O)[13CH]=[13CH]3)N)=O)([H])SC1(C)C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Geddes AM, et al. Introduction: historical perspective and development of amoxicillin/clavulanate. Int J Antimicrob Agents. 2007 Dec;30 Suppl 2:S109-12.  [Content Brief]

  [3]. Handsfield HH,et al. Amoxicillin, a new penicillin antibiotic. Antimicrob Agents Chemother. 1973 Feb;3(2):262-5.  [Content Brief]