2. Isotope-Labeled Compounds
  3. Internal Standard for Pesticides & Veterinary Medicine

Internal Standard for Pesticides & Veterinary Medicine

Agricultural products containing pesticide and veterinary drug residues do not mean that they are absolutely unsafe, but whether they will affect human health depends on whether the residue exceeds the standard. Only when the residue exceeds the national testing standards will it have a negative impact on the health of human. For the quantitative detection of residues, isotope-labeled internal standards play their unique advantages. MedChemExpress (MCE) provides a wide variety of isotope-labeled compounds for pesticide and veterinary drug residues to meet different scientific research needs[1].

 

References:

[1] J Hazard Mater. 2022 May 15;430:128413.

Internal Standard for Pesticides & Veterinary Medicine (573):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
    Estradiol-d<sub>4</sub>
  • HY-B0413S
    Fenbendazole-d3 1228182-47-5 99.46%
    Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].
    Fenbendazole-d<sub>3</sub>
  • HY-66005S
    Acetaminophen-d4 64315-36-2 99.60%
    Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].
    Acetaminophen-d<sub>4</sub>
  • HY-13678S
    Meropenem-d6 1217976-95-8 ≥98.0%
    Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
    Meropenem-d<sub>6</sub>
  • HY-13571S1
    Betamethasone dipropionate-d5
    Betamethasone dipropionate-d5 (Betamethasone 17,21-dipropionate-d5) is deuterium-labeled Betamethasone dipropionate (HY-13571).
    Betamethasone dipropionate-d5
  • HY-100935S
    Cimaterol-d7 1228182-44-2
    Cimaterol-d7 is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.
    Cimaterol-d<sub>7</sub>
  • HY-17382S
    Metoclopramide-d3 1216522-89-2
    Metoclopramide-d3 is deuterium labeled Metoclopramide. Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. Metoclopramide can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis[1][2].
    Metoclopramide-d<sub>3</sub>
  • HY-B0322S
    Sulfamethoxazole-d4 1020719-86-1 99.56%
    Sulfamethoxazole-d4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic[1].
    Sulfamethoxazole-d<sub>4</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 99.91%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-Y0271S2
    Urea-13C,15N2 58069-83-3 99.10%
    Urea-13C,15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-B1618S1
    Corticosterone-d4 2243253-91-8 99.17%
    Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>4</sub>
  • HY-B0167S
    Salicylic acid-d6 285979-87-5 99.83%
    Salicylic acid-d6 is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
    Salicylic acid-d<sub>6</sub>
  • HY-17506S
    Azithromycin-d3 163921-65-1
    Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].
    Azithromycin-d<sub>3</sub>
  • HY-B0141S
    Estradiol-d3 79037-37-9 98.60%
    Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>3</sub>
  • HY-18569S3
    3-Indoleacetic acid-d7 1173020-21-7 ≥99.00%
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-d<sub>7</sub>
  • HY-B0125S
    Ofloxacin-d3 1173147-91-5 99.77%
    Ofloxacin-d3 is the deuterium labeled Ofloxacin[1].
    Ofloxacin-d<sub>3</sub>
  • HY-B0510S
    Trimethoprim-d9 1189460-62-5 98.81%
    Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].
    Trimethoprim-d<sub>9</sub>
  • HY-B0322S1
    Sulfamethoxazole-13C6 1196157-90-0 99.65%
    Sulfamethoxazole-13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA)[1].
    Sulfamethoxazole-<sup>13</sup>C<sub>6</sub>
  • HY-B0151S2
    Pregnenolone-d4-1 61574-54-7 99%
    Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
    Pregnenolone-d<sub>4</sub>-1