1. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  2. Mesothelin ADC Antibody
  3. Anetumab

Anetumab  (Synonyms: Anti-MSLN Antibody)

Cat. No.: HY-P99352 Purity: 98.78%
Technical Support

Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No. : 1954758-84-9

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Based on 1 publication(s) in Google Scholar

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Description

Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer[1].

Isotype

Human IgG1 lambda

Recommend Isotype Controls
Species

Human

In Vitro

Anetumab ravtansine (HY-141606) is composed of Anetumab and the microtubule-targeting toxin DM4 (HY-12454) linked by a reducible disulfide bond[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

143660.00

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anetumab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 lambda
Biological Activity
  • Immobilized Mesothelin Protein, Human (303a.a, HEK293, His, HY-P70148) can bind Anetumab. The EC50 for this effect is 4.33 ng/mL.
Purity & Documentation

Purity: 98.78%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anetumab
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HY-P99352
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