2. Neuronal Signaling Protein Tyrosine Kinase/RTK
  3. Monoamine Oxidase DYRK
  4. AnnH31

AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM.

For research use only. We do not sell to patients.

AnnH31 Chemical Structure

AnnH31 Chemical Structure

CAS No. : 241809-12-1

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1 mg USD 260 In-stock
5 mg USD 640 In-stock
10 mg USD 890 In-stock
25 mg USD 1400 In-stock
50 mg USD 1850 In-stock
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Based on 1 publication(s) in Google Scholar

AnnH31 Related Antibodies

Top Publications Citing Use of Products

View All Monoamine Oxidase Isoform Specific Products:

View All Isoforms
MAO-A MAO-B

View All DYRK Isoform Specific Products:

View All Isoforms
DYRK1 DYRK2 DYRK3 DYRK4

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM[1].

IC50 & Target

81 nM (Dyrk1A), 3.2 μM (MAO-A)[1]
Molecular Weight

251.28

Formula

C15H13N3O
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

N#CCN1C2=C(C3=C1C=C(C=C3)OC)C=CN=C2C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (497.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9796 mL 19.8981 mL 39.7962 mL
5 mM 0.7959 mL 3.9796 mL 7.9592 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9796 mL 19.8981 mL 39.7962 mL 99.4906 mL
5 mM 0.7959 mL 3.9796 mL 7.9592 mL 19.8981 mL
10 mM 0.3980 mL 1.9898 mL 3.9796 mL 9.9491 mL
15 mM 0.2653 mL 1.3265 mL 2.6531 mL 6.6327 mL
20 mM 0.1990 mL 0.9949 mL 1.9898 mL 4.9745 mL
25 mM 0.1592 mL 0.7959 mL 1.5918 mL 3.9796 mL
30 mM 0.1327 mL 0.6633 mL 1.3265 mL 3.3164 mL
40 mM 0.0995 mL 0.4975 mL 0.9949 mL 2.4873 mL
50 mM 0.0796 mL 0.3980 mL 0.7959 mL 1.9898 mL
60 mM 0.0663 mL 0.3316 mL 0.6633 mL 1.6582 mL
80 mM 0.0497 mL 0.2487 mL 0.4975 mL 1.2436 mL
100 mM 0.0398 mL 0.1990 mL 0.3980 mL 0.9949 mL
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AnnH31 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AnnH31241809-12-1AnnH 31AnnH-31Monoamine OxidaseDYRKMAODual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseDyrk1A inhibitionMAO-A inhibitionInhibitorinhibitorinhibit

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HY-129449
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