2. NF-κB Immunology/Inflammation Apoptosis
  3. NF-κB COX TNF Receptor
  4. Anti-inflammatory agent 20

Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation.

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Anti-inflammatory agent 20 Chemical Structure

Anti-inflammatory agent 20 Chemical Structure

CAS No. : 2127403-65-8

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Anti-inflammatory agent 20 Related Antibodies

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Description

Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].

IC50 & Target

NF-κB

 

COX-2

 

Molecular Weight

690.95

Formula

C39H66N2O8
CAS No.
SMILES

[H][C@@]12[C@H](CC[C@]1([C@@]3(CC[C@]4(C(C)([C@H](CC[C@@]4([C@]3(C[C@H]2O)[H])C)OC(CNC(CNC(OC(C)(C)C)=O)=O)=O)C)[H])C)C)[C@@]5(CC[C@@H](O5)C(C)(O)C)C
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Anti-inflammatory agent 20 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 202127403-65-8NF-κBCOXTNF ReceptorNuclear factor-κBNuclear factor-kappaBCyclooxygenaseTumor Necrosis Factor ReceptorTNFROcotillol-type sapogeninsOTS derivativeGinsenosidesAnti-inflammatory activityMAPK pathwaynitric oxide inhibitionInhibitorinhibitorinhibit

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Anti-inflammatory agent 20
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