2. Immunology/Inflammation Apoptosis NF-κB
  3. Interleukin Related TNF Receptor NF-κB
  4. Anti-inflammatory agent 41

Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway.

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Anti-inflammatory agent 41 Chemical Structure

Anti-inflammatory agent 41 Chemical Structure

CAS No. : 2896204-90-1

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Anti-inflammatory agent 41 Related Antibodies

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Description

Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].

In Vitro

Anti-inflammatory agent 41 (13a) significantly reduced the LPS-induced nuclear translocation of p65 in J774A.1 macrophages[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-inflammatory agent 41 Related Antibodies
Molecular Weight

543.57

Formula

C33H25N3O5
CAS No.
SMILES

COC1=CC2=C(C(OC3=CC=C(C=C3)NC(C4=CN(C5=CC=CC=C5C4=O)C6=CC=CC=C6)=O)=CC=N2)C=C1OC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-inflammatory agent 41 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 412896204-90-1Interleukin RelatedTNF ReceptorNF-κBILTumor Necrosis Factor ReceptorTNFRNuclear factor-κBNuclear factor-kappaBAnti-inflammatoryLPSIL-6TNF-αInhibitorinhibitorinhibit

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Anti-inflammatory agent 41
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HY-149816
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