1. Anti-infection
  2. Bacterial
  3. Anti-MRSA agent 18

Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death.

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Anti-MRSA agent 18 Chemical Structure

Anti-MRSA agent 18 Chemical Structure

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Description

Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death[1].

Molecular Weight

715.55

Formula

C36H42BrCl2N3O3

SMILES

C=CCC1=C(C=CC(C2=C3OC(C4=C(C=CC=C4Cl)Cl)=NC3=CC(CC=C)=C2)=C1)OCCC[N+](C)(CC(NCCCC)=O)C.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Anti-MRSA agent 18 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-MRSA agent 18
Cat. No.:
HY-169160
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