2. Apoptosis
  3. Apoptosis
  4. Anti-osteoporosis agent-1

Anti-osteoporosis agent-1 (comp 4aa) is a potent replication protein A (RPA) inhibitor (IC50=18 µM) .

For research use only. We do not sell to patients.

Anti-osteoporosis agent-1 Chemical Structure

Anti-osteoporosis agent-1 Chemical Structure

CAS No. : 2761577-50-6

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Anti-osteoporosis agent-1 Related Antibodies

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Description

Anti-osteoporosis agent-1 (comp 4aa) is a potent replication protein A (RPA) inhibitor (IC50=18 µM) [1].

In Vitro

Anti-osteoporosis agent-1 is an active molecule which showed effective mineralisation of osteoblast cells and up regulates the osteogenic marker gene such as Bmp-2, Runx-2 and Type-1col at both transcriptional and translational level. Besides exhibiting potential osteogenic activity. In addition, Anti-osteoporosis agent-1 also own significant anti-apoptotic activity at 1 pM &100 pM concentration and increases the osteoblast survival in serum deprived conditions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-osteoporosis agent-1 Related Antibodies
Molecular Weight

354.83

Formula

C20H19ClN2O2
CAS No.
SMILES

CC1(C=CC2=C(C(C3=NNC(C3)C4=CC=C(C=C4)Cl)=C(C=C2)O)O1)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-osteoporosis agent-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-osteoporosis agent-12761577-50-6ApoptosisosteoporosisBmp-2Runx-2RPAInhibitorinhibitorinhibit

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