2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 118

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

Antibacterial agent 118 Chemical Structure

Antibacterial agent 118 Chemical Structure

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Antibacterial agent 118 Related Antibodies

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Description

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis[1].

IC50 & Target

IC50: 68 µM (Hep G2)[1]
In Vitro

Antibacterial agent 118 (1-1000 µM; 24 h) shows cytotoxicity towards Hep G2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 118 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: Hep G2 cell line
Concentration: 1-1000 µM
Incubation Time: 24 hours
Result: Inhibited Hep G2 cells growth with IC50 value of 68 µM.
Molecular Weight

383.47

Formula

C19H21N5O2S
SMILES

O=C(C1=NC=CN=C1NC([C@]2(CC3C4)C[C@@H]4CC(C3)C2)=O)NC5=NC=CS5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 118 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 118Antibacterial agent118Antibacterial agent-118BacterialtuberculosisfungalbacteriaHep G2MICcytotoxicityaminothiazolepyrazineInhibitorinhibitorinhibit

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