2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 143

Antibacterial agent 143 (Compound 5a) is an antibacterial agent with MICs of 25, 25, 50 and 50 μg/mL against B. subtilis ATCC6633, S. aureus ATCC6538, P. aeruginosa ATCC13525 and E. coli ATCC35218, respectively.

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Antibacterial agent 143 Chemical Structure

Antibacterial agent 143 Chemical Structure

CAS No. : 299405-68-8

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Antibacterial agent 143 Related Antibodies

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Description

Antibacterial agent 143 (Compound 5a) is an antibacterial agent with MICs of 25, 25, 50 and 50 μg/mL against B. subtilis ATCC6633, S. aureus ATCC6538, P. aeruginosa ATCC13525 and E. coli ATCC35218, respectively[1].

Molecular Weight

373.27

Formula

C17H13BrN2OS
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(CC1=CC=CC=C1)NC2=NC(C3=CC=C(Br)C=C3)=CS2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (267.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6790 mL 13.3951 mL 26.7903 mL
5 mM 0.5358 mL 2.6790 mL 5.3581 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6790 mL 13.3951 mL 26.7903 mL 66.9756 mL
5 mM 0.5358 mL 2.6790 mL 5.3581 mL 13.3951 mL
10 mM 0.2679 mL 1.3395 mL 2.6790 mL 6.6976 mL
15 mM 0.1786 mL 0.8930 mL 1.7860 mL 4.4650 mL
20 mM 0.1340 mL 0.6698 mL 1.3395 mL 3.3488 mL
25 mM 0.1072 mL 0.5358 mL 1.0716 mL 2.6790 mL
30 mM 0.0893 mL 0.4465 mL 0.8930 mL 2.2325 mL
40 mM 0.0670 mL 0.3349 mL 0.6698 mL 1.6744 mL
50 mM 0.0536 mL 0.2679 mL 0.5358 mL 1.3395 mL
60 mM 0.0447 mL 0.2233 mL 0.4465 mL 1.1163 mL
80 mM 0.0335 mL 0.1674 mL 0.3349 mL 0.8372 mL
100 mM 0.0268 mL 0.1340 mL 0.2679 mL 0.6698 mL
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Antibacterial agent 143 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 143299405-68-8Antibacterial agent143Antibacterial agent-143BacterialInhibitorinhibitorinhibit

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