1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 202

Antibacterial agent 202 (compound 45c) is a low cytotoxicity bacterial inhibitor with good activity against Gram-negative bacteria, including Escherichia coli, Klebsiella pneumonia, especially Pseudomonas aeruginosa, (MIC (minimum inhibitory concentration)=7.8-31.25 μM). Antibacterial agent 202 can exert antibacterial activity by destroying the integrity of cell membranes and can be used in the research of bacterial infections.

For research use only. We do not sell to patients.

Antibacterial agent 202 Chemical Structure

Antibacterial agent 202 Chemical Structure

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Description

Antibacterial agent 202 (compound 45c) is a low cytotoxicity bacterial inhibitor with good activity against Gram-negative bacteria, including Escherichia coli, Klebsiella pneumonia, especially Pseudomonas aeruginosa, (MIC (minimum inhibitory concentration)=7.8-31.25 μM). Antibacterial agent 202 can exert antibacterial activity by destroying the integrity of cell membranes and can be used in the research of bacterial infections[1].

In Vitro

Antibacterial agent 202 (12.5-50 μM; 24-72 h) exhibits antibacterial efficacy in C. Elegans infection model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: P. aeruginosa PAO1-infected C. elegans model
Concentration: 12.5, 25, 50 μM
Incubation Time: 24, 48, 72 h
Result: Increased the survival rate of C. elegans to 50% after 72 h.
Molecular Weight

606.68

Formula

C34H39FN2O7

SMILES

O=C(O)C1=C(/C=C/C2=CC=C(F)C=C2)C=C(OCCCCCCC(NCC3=CC(C(O)=CN3C)=O)=O)C(C/C=C(C)/C)=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Antibacterial agent 202 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Antibacterial agent 202
Cat. No.:
HY-161404
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