2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 96

Antibacterial agent 96 (compound 4k) is a potent antibacterial agent. Antibacterial agent 96 shows antitubercular activity against agent-susceptible and multidrug-resistantMycobacterium tuberculosis (M. tuberculosis) strains. Antibacterial agent 96 shows toxicity to HepG2 and Vero cells.

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Antibacterial agent 96 Chemical Structure

Antibacterial agent 96 Chemical Structure

CAS No. : 2413006-62-7

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Antibacterial agent 96 Related Antibodies

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Description

Antibacterial agent 96 (compound 4k) is a potent antibacterial agent. Antibacterial agent 96 shows antitubercular activity against agent-susceptible and multidrug-resistantMycobacterium tuberculosis (M. tuberculosis) strains. Antibacterial agent 96 shows toxicity to HepG2 and Vero cells[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 CC50
14.4 μM
Compound: 4k
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 32113048]
HepG2 CC50
14.9 μM
Compound: 4k
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
[PMID: 32113048]
Vero CC50
> 20 μM
Compound: 4k
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 32113048]
Vero CC50
> 20 μM
Compound: 4k
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
[PMID: 32113048]
In Vitro

Antibacterial agent 96 shows antibacterial activity with an MIC value of 0.3, 0.2, 0.5, 0.2, 14.4 μM for Mycobacterium tuberculosis (M. tuberculosis) H37RvPT2, PT12, PT20, qcrB-T313A strain, respectively[1].
Antibacterial agent 96 shows toxicity with CC50s of 14.4, >20 μM for HepG2 and Vero cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 96 Related Antibodies
Molecular Weight

348.22

Formula

C18H15Cl2NO2
CAS No.
SMILES

COC1=CC2=C(N=C(C=C2OCC3=CC=C(C(Cl)=C3)Cl)C)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 96 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 962413006-62-7Antibacterial agent96Antibacterial agent-96BacterialantibacterialantitubercularHepG2Vero cellsMycobacterium tuberculosisInhibitorinhibitorinhibit

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