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  2. Primary Antibodies
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  4. CD11b Antibody (YA3423)

CD11b Antibody (YA3423)

Cat. No.: HY-P83690
COA User Guide for Antibodies

CD11b Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 127 kDa, targeting to CD11b. It can be used for WB,IHC-P,ICC/IF,FC,IP assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $80 In-stock
50 μL $200 In-stock
100 μL $325 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

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Description

CD11b Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 127 kDa, targeting to CD11b. It can be used for WB,IHC-P,ICC/IF,FC,IP assays with tag free, in the background of Human.

Background

CD11b: Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development; endocytosis; and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system; heart; lymphatic vessel; thymus; and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M). [provided by Alliance of Genome Resources, Apr 2022]

Gene ID

16409

Synonyms
CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; CD11b; Leukocyte adhesion receptor MO1
Molecular Weight

Predicted band size: 127 kDa;Observed band size: 170 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Neuroscience

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

P11215

Dilution Ratio

WB: 1/500-1/1000; IHC: 1/50-1/100; IF: 1/50-1/200; IP: 1/50; FC: 1/50-1/100;

Application

WB, IHC-P, ICC/IF, IP, FC

Appearance

Liquid

Formulation

Supplied in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human CD11b

Documentation

CD11b Antibody (YA3423) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD11b Antibody (YA3423)
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HY-P83690
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