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  4. CD45 Antibody (YA800)

CD45 Antibody (YA800)

Cat. No.: HY-P80603
COA User Guide for Antibodies

CD45 Antibody (YA800) is a non-conjugated and Mouse origined monoclonal antibody about 147 kDa, targeting to CD45. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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Description

CD45 Antibody (YA800) is a non-conjugated and Mouse origined monoclonal antibody about 147 kDa, targeting to CD45. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.

Background

CD45: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Tag

Free

Gene ID

5788

Synonyms
PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
Molecular Weight

Predicted band size: 147 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Immunology

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Mouse

SwissProt ID

P08575

Dilution Ratio

WB: 1:500-1:1,000 ;IHC: 1:50-1:100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human PTPRC.AA range:928-989.

Documentation

CD45 Antibody (YA800) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD45 Antibody (YA800)
Cat. No.:
HY-P80603
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