eIF4G1 Antibody

eIF4G1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 175 kDa, targeting to eIF4G1. It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human.

eIF4G1: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]

Free

1981

Predicted band size: 175 kDa

affinity purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human

Q04637

WB: 1:500-1:1,000 ;IHC: 1:50-1:100 ;IF: 1:50-1:200

WB, IHC-P, ICC/IF

Liquid

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Synthetic peptide corresponding to Human eIF4G.AA range:.1230-1234.