Fibulin 5 Antibody (YA2448)

Fibulin 5 Antibody (YA2448) is a biotin-conjugated non-conjugated IgG antibody, targeting Fibulin 5, with a predicted molecular weight of 50 kDa (observed band size: 50 kDa). Fibulin 5 Antibody (YA2448) can be used for WB experiment in human, mouse background.

The protein encoded by The related gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by The related gene may play a role in vascular development and remodeling. Defects in The related gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular derelated generation type 3 (ARMD3).

10516

Predicted band size: 50 kDa; Observed band size: 50 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

Q9UBX5

WB: 1/500-1/1000

WB

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Fibulin 5