GAD67 Antibody (YA1807)

GAD67 Antibody (YA1807) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1807), targeting GAD67, with a predicted molecular weight of 67 kDa (observed band size: 67 kDa). GAD67 Antibody (YA1807) can be used for WB, IP experiment in human background.

The related gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for The enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. The related gene may also play a role in the stiff man syndrome. Deficiency in The enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of The related gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

2571

Predicted band size: 67 kDa; Observed band size: 67 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q99259

WB: 1/500-1/1000;IP: 1/20

WB, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human GAD67